SCIENCE & ARTICLES The path to discovery — the life changing power of cellular & metabolic rejuvenation.

The Fasting Mimicking Nutrition Technology is at the core of the health benefits of Prolon products. This precision nutrition formulation nourishes the body while keeping its metabolism and cells in fasting mode and therefore harvesting the health benefits of fasting while eating plant based, clean, premium nutrition. The Fasting Mimicking Nutrition was developed at the Longevity Institute of the University of Southern California and at L-Nutra Inc. by a global team of Longevity experts led by Professor Valter Longo (TIME Top 50 Most Influential People in Health).

Prolon's Fasting Mimicking Nutrition is now tested independently in over 32 human trials conducted at 18 university research centers such as Stanford, Mayo Clinic, University of Miami, University of Indiana, University of Genoa, Leiden University, Heidelberg University, University of Palermo and many others, for applications in longevity, prevention and disease remission (Diabetes, Cancer, Cardiovascular, Inflammation and others). These studies have helped tremendously in furthering Prolon's leadership in Nutrition for Longevity and Food as Medicine and have demonstrated major life changing benefits. Most of these trials include a protocol 3 to 6 Prolon 5-Day Fasting Mimicking Diet per year.

Below are some of the scientific and medical articles published on the Fasting Mimicking Diet.

Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease: controlled trial
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease: controlled trial
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
Fasting-Mimicking-Diet does not reduce skeletal muscle function in healthy young adults: a randomized control trial
Fasting-Mimicking-Diet does not reduce skeletal muscle function in healthy young adults: a randomized control trial
Fasting Mimicking Diet Cycles vs a Mediterranean Diet and Cardiometabolic Risk in Overweight and Obese Hypertensive Subjects: A Randomized Clinical Trial
Fasting Mimicking Diet Cycles vs a Mediterranean Diet and Cardiometabolic Risk in Overweight and Obese Hypertensive Subjects: A Randomized Clinical Trial
The Effects of a Fasting Mimicking Diet on Skin Hydration, Skin Texture, and Skin Assessment: A Randomized Controlled Trial
The Effects of a Fasting Mimicking Diet on Skin Hydration, Skin Texture, and Skin Assessment: A Randomized Controlled Trial
Six-Month Periodic Fasting in Patients With Type 2 Diabetes and Diabetic Nephropathy: A Proof-of-Concept Study
Six-Month Periodic Fasting in Patients With Type 2 Diabetes and Diabetic Nephropathy: A Proof-of-Concept Study
Efficacy of a fasting-mimicking diet in functional therapy for depression: A randomised controlled pilot trial
Efficacy of a fasting-mimicking diet in functional therapy for depression: A randomised controlled pilot trial
Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality
Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality
An Intermittent Fasting Mimicking Nutrition Bar Extends Physiologic Ketosis in Time Restricted Eating: A Randomized, Controlled, Parallel-Arm Study
An Intermittent Fasting Mimicking Nutrition Bar Extends Physiologic Ketosis in Time Restricted Eating: A Randomized, Controlled, Parallel-Arm Study
Association between IGF-1 levels ranges and all-cause mortality: A meta-analysis
Association between IGF-1 levels ranges and all-cause mortality: A meta-analysis
Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan
Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan
Fasting and cancer treatment in humans: A case series report
Fasting and cancer treatment in humans: A case series report
Fasting-mimicking diet and hormone therapy induce breast cancer regression
Fasting-mimicking diet and hormone therapy induce breast cancer regression
Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence
Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence
Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology
Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
Prolonged Fasting reduces IGF-1/PKA to promote hematopoietic stem cell-based regeneration and reverse immunosuppression
Prolonged Fasting reduces IGF-1/PKA to promote hematopoietic stem cell-based regeneration and reverse immunosuppression
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms
Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes
Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes

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