4.4
1M+ Happy Healthy Customers

Prolon 5-Day Fasting
Mimicking Diet

Starting at
A patented, science-backed program that keeps your body in a fasting state while allowing you to eat nourishing foods. Over five days, your body is rejuvenated at the cellular level, supporting longevity and unlocking powerful health benefits including:
Fat loss with muscle protection

Cellular rejuvenation

Improved relationship with food

Renewed energy and mental clarity 

A complete body reset

A Prolon exclusive

For a limited time receive a free one-month Classpass membership, plus 50 bonus credits with your Prolon 5-Day purchase.

What’s inside the box?

The Prolon FMD includes everything you need for your five days of renewal. Just follow the meal guide and eat and drink what’s in each day’s box. The foods in each box are designed to nourish your body while staying below nutrient sensing pathways, so you stay in a fasting state, and get all the benefits of fasting. Learn more about what’s inside each kit below.

HSA/FSA eligible

Pay for your Prolon purchase with qualifying HSA/FSA funds.

Programs like health savings accounts (HSA) and flexible spending accounts (FSA) enable individuals to allocate pre-tax money for qualified healthcare expenses. Prolon has partnered with Sika, allowing customers to use their HSA/FSA funds to purchase our science backed products.

  • Choose pay with Sika at checkout or learn more here.

ADD THE ESSENTIALS:

L-Protein

L-Protein

26g of plant-based protein

$45.00 $50.00
Fasting Shake

Fasting Shake

Nourish your body and fast for longer

$59.99 $69.99
1-Day Reset

1-Day Reset

A complete day of fasting nutrition

$34.99 $39.99

One program.
Many benefits.

Fat-focused weight loss

Unlike many weight loss products and drugs, Prolon allows you to lose visceral fat while protecting muscle.

Mental clarity and focus

Prolon activates ketosis, a fat-burning state known for brain-boosting benefits—many users report better focus and mental clarity post-fast.

Healthy aging through cellular rejuvenation

Research shows that three consecutive monthly cycles of the Fasting Mimicking Diet can reduce your biological age.

Renewed energy

With cells refreshed after completing the 5-day cycle, many users report improved energy levels and vitality after the fast. 

Metabolic reset

20 days of Prolon is as effective as 120 days of the Mediterranean diet on heart health, and supports healthy metabolic markers.

Improved skin health and radiance

Three consecutive cycles of Prolon 5-Day can lead to increased skin hydration and a more radiant complexion.

REJUVENATION FROM THE INSIDE OUT

Prolon 5-Day Nutrition Program

On each day of the program, powerful changes are happening inside your body that can have a profound effect on your health. 

DAY 1

Transition to a
fasting state

Today, your body starts adapting to reduced calorie intake, depleting glucose stores (your primary energy source) and paving the way for fat-burning and cellular benefits. 

START YOUR PROGRAM
DAY 2

Ketosis

For most, fat-burning is in full effect! By now, your glucose stores are depleted, and your body is fully transitioning to burning fat for energy, or ketosis. 

START YOUR PROGRAM
DAY 3

Autophagy

By now, something incredible is happening—your body is transitioning to autophagy, the natural process that eliminates and recycles old, damaged cells. 

START YOUR PROGRAM
DAY 4

Cellular
rejuvenation

Your body is now in a heightened state of cellular rejuvenation, with autophagy in full swing, actively repairing and renewing cells. Fat burning is also at its peak.

START YOUR PROGRAM
DAY 5

Deep renewal
and change

Your body has undergone a significant transformation: Autophagy recycled old cells to replace them with younger, high-functioning components. These cells now function as younger versions of themselves, supporting lasting benefits.

START YOUR PROGRAM

What’s in the box

Soups

A variety of our original powdered soups made with a proprietary mix of all-natural, plant-based ingredients. Soup flavors include favorites like Minestrone, Tomato, Mushroom, Vegetable, and Minestrone Quinoa

Nut Bars

Cold-pressed, delicious nut bars with whole ingredients like almonds, macadamia nuts, and pecans.

Snacks

Snacks like olives from the South of Spain where olive consumption is associated with longevity, and kale crackers enriched with plant-based protein.

L-Drink

Fruit-flavored, proprietary glycerol mix designed to fuel and protect muscles throughout the fast.

Supplements

Dietary supplement packed with multivitamins, minerals and omega-3 fatty acid to provide the body with nourishment.

Herbal Teas

Caffeine-free herbal teas loaded with healthy antioxidants, and will keep you hydrated during your week.

Soups

A variety of our original powdered soups made with a proprietary mix of all-natural, plant-based ingredients. Soup flavors include Red Bell Pepper & Onion, Green Pea & Chives, Lentil Curry, Chickpea & Leeks, and Carrot Ginger.

Nut Bars

Cold-pressed, delicious nut bars with whole ingredients like almonds, macadamia nuts, and pecans.

Snacks

Snacks like olives from the South of Spain where olive consumption is associated with longevity, and kale crackers enriched with plant-based protein.

L-Drink

Fruit-flavored, proprietary glycerol mix designed to fuel and protect muscles throughout the fast.

Supplements

Dietary supplement packed with multivitamins, minerals and omega-3 fatty acid to provide the body with nourishment.

Herbal Teas

Caffeine-free herbal teas loaded with healthy antioxidants, and will keep you hydrated during your week.

Soups and Extra Virgin Olive Oil

A variety of easy-to-prepare soups made with a proprietary mix of all-natural, plant-based ingredients. Includes a mix of our classic and bold soup flavors like Minestrone, Tomato, Chickpea & Leeks, Carrot Ginger, Red Pepper & Onion, Lentil Curry.

Extra virgin olive oil packets to add to your soups, for added taste & texture

Nut Bars

Cold-pressed, delicious nut bars with whole ingredients like almonds, macadamia nuts, and pecans. This kit includes Fasting Bars in place of the L-Bar for added variety.

Snacks

Snacks like olives from the South of Spain where olive consumption is associated with longevity, and kale crackers enriched with plant-based protein.

L-Drink

Fruit-flavored, proprietary glycerol mix designed to fuel and protect muscles throughout the fast.

Supplements

Dietary supplement packed with multivitamins, minerals and omega-3 fatty acid to provide the body with nourishment.

Herbal Teas

Caffeine-free herbal teas loaded with healthy antioxidants, and will keep you hydrated during your week.

Soups

A variety of ready-to-eat soups made with a proprietary mix of all-natural, plant-based ingredients. Next Gen soups are made with all organic ingredients and designed for busy lifestyles. Simply pour from the package, heat, and eat (you can also enjoy them cold).

Nut Bars

Cold-pressed, delicious nut bars with whole ingredients like almonds, macadamia nuts, and pecans.

Snacks

Snacks like olives from the South of Spain where olive consumption is associated with longevity, and kale crackers enriched with plant-based protein.

L-Drink

Fruit-flavored, proprietary glycerol mix designed to fuel and protect muscles throughout the fast.

Supplements

Dietary supplement packed with multivitamins, amino-acids, minerals and omega-3 fatty acid to provide the body with nourishment.

Herbal Teas

Organic, caffeine-free herbal teas with healthy antioxidants help the body detoxify and stay hydrated during your fast.

Live younger.  Age slower.

2 years 1 year years 0.0

With three cycles of Prolon—just 15 days—you can actually reverse your biological age by 2.5 years. It’s a complete reset that enhances your healthspan, and helps you take control of how you age.

1,000,000+ Happy Healthy Customers

Backed by science, loved by users

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“It works—weight management, energy, and mental clarity.”

- Zaree

Verified Reviewer

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"I lost 5 pounds my first round and felt amazing."

- Amy

Verified Reviewer

Not just weight loss—weight care
Getting to a healthy weight is critical for your health. And when you’re looking to lose weight it’s important to keep in mind that you want to lose fat, not muscle.
With GLP-1 drugs and some other diets, you don’t just lose weight—you lose muscle mass. And this can cause your body to become less effective at keeping that weight off.
Prolon’s 5-Day Program helps you lose visceral fat, while you preserve lean muscle mass.

A complete system for healthy aging

By mimicking fasting states, the clinically tested FMD initiates cellular rejuvenation, and targets visceral fat. It's your periodic deep clean and systemic overhaul.

Our approach to daily nutrition is grounded in decades of longevity research. These are products that support healthspan and make it easier to eat for longevity, every day.

FAQs

The Prolon 5-Day FMD kit contains five small boxes, each labeled for one of the five days of the program. Each day's box contains all the food, beverages, and supplements you'll consume for that specific day—you’ll see all the items laid out in the meal card included in the kit. We’ve made suggestions as to which items you may consume for breakfast, lunch, dinner, and snacks, but the order in which you consume each day’s items is up to you. However, don’t switch items from one day to another, as each day’s plan is precisely calibrated to activate different phases of cellular renewal.
When you do a cycle of Prolon, something remarkable happens in your body— autophagy. Autophagy is the body's natural cellular cleansing and repair process. During this state, the body breaks down and recycles damaged components to enhance efficiency, generate energy, and support new cell growth. Recognized for its role in slowing aging, reducing inflammation, and protecting against diseases like cancer and neurodegeneration, autophagy was the subject of the 2016 Nobel Prize for Physiology or Medicine. Autophagy is typically activated after 72 hours of nutrient deprivation; the Prolon program was designed to activate autophagy by providing scientifically developed foods that stay below the body's nutrient-sensing pathways, allowing it to maintain a fasting state. Once autophagy clears out cellular debris, the body makes way for younger, higher-functioning cells. These vibrant cells help improve efficiency, support healthy metabolic markers, and slow the aging process—a transformation known as cellular reprogramming.
Prolon provides the body with a scientifically developed, naturally occurring combination of macronutrients (fats, carbohydrates, proteins) and micronutrients (essential vitamins and minerals) designed to keep the body nourished while giving it the benefits of fasting. Each day of the Fasting Mimicking Program is structured to activate different phases of cellular renewal.

Here’s what’s happening inside:

Day 1: Transition to a fasting state Today, your body starts adapting to reduced calorie intake, depleting glucose stores (your primary energy source) and paving the way for fat-burning and cellular benefits. As your body shifts into fasting mode, you might notice cravings or fatigue, but these sensations are short-lived as your system adapts.

Day 2: Ketosis For most, fat-burning is in full effect! By now, your glucose stores are depleted, and your body is fully transitioning to burning fat for energy, or ketosis. Unlike traditional fasts that can lead to muscle loss, Prolon is designed to protect lean muscle while supporting fat burning. As the adjustment continues, you may experience temporary symptoms like brain fog, headaches, or fatigue. Some gastrointestinal discomfort is also normal due to Prolon’s high fiber content. These are all signs of your body adapting—and they’ll soon pass!

Day 3: Autophagy By now, something incredible is happening—your body is transitioning to autophagy, the natural process that eliminates and recycles old, damaged cells. This powerful repair mechanism helps pave the way for cellular renewal, fostering more efficient cells that support healthy aging (both inside and out!) Today might feel more challenging, but remember that any symptoms you experience are signs of deep cellular transformation at work.

Day 4: Cellular rejuvenation Your body is now in a heightened state of cellular rejuvenation, with autophagy in full swing, actively repairing and renewing cells. Fat burning is also at its peak, providing a steady, efficient energy source. These powerful processes are working together to revitalize your body, and their benefits will continue to build—even beyond the completion of the program. Some participants experience "keto-euphoria" at this stage, an increase in mental clarity, focus, energy, and vitality. Hunger often diminishes, making the fast feel easier.

Day 5: Deep renewal and change Your body has undergone a significant transformation: Autophagy recycled and removed old cells to replace them with younger, high-functioning components. These cells now function as younger versions of themselves, supporting lasting benefits. On Day 5, you may wake up feeling sharper, recharged, and lighter, with a renewed sense of energy and a change on the scale—a testament to all the amazing work your body has done.

What’s next? Even though your 5-day program is complete, the benefits of autophagy continue well into Day 7! Day 6 is your transition day, and we suggest beginning with small, light, or liquid meals introducing foods back in slowly: for breakfast, try an L-Protein smoothie, toast with L-Spread, or buckwheat porridge. Lunch might include a veggie bowl with beans and avocado, while dinner could feature salmon, rice, and broccoli. By Day 7, you can gradually return to your normal diet. To maintain Prolon’s benefits and support your healthy aging, we recommend following the principles outlined in The Longevity Diet. Based on the eating patterns of those in areas with the largest concentration of people living healthily into their hundreds, it focuses on primarily plant-based eating with balanced amounts of protein.
While the purpose of the Prolon program is to trigger rejuvenation, weight loss can be another benefit for those who are looking to manage their weight. Everyone is different, and weight loss depends on a number of factors. The average weight loss for program users is about five pounds after one cycle. And the program has been shown to reduce waist circumference by 1.5 inches after three cycles. What’s most important is the kind of weight loss you experience doing the program. The FMD is proven to target visceral fat while protecting muscle. This is in contrast to extreme diets and weight loss drugs that result in substantial muscle loss along with weight loss. And with Prolon, weight loss is sustained even after returning to normal diet
While there are many different signaling factors in the “nutrient-sensing pathways” involved with cellular fasting, the three primary nutrient-sensing pathways that Prolon and fasting down-regulate are IGF-1, mTOR, and PKA. The process is complex, and each pathway can interact with other pathways, but in general, PKA responds primarily to sugar and carbohydrates, while IGF-1 is primarily responsive to protein (and more strongly triggered by animal protein), and mTOR is triggered by IGF-1 and amino acids. Sugar and carbohydrates (and to some extent caffeine) will activate PKA. These nutrient-sensing pathways all help regulate the cells’ growth cycles and stress-resistant “fasting” state.
Day 1 has about 1100 calories (kcals), while Days 2-5 have between 700 and 800 calories (kcals) per day.

Do you have a metabolic condition?

Learn more about our clinical Prolon program.

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Are you a healthcare practitioner?

Learn more about using Prolon in your practice.

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