Path to Healthspan: The Life-Changing
Our on-going commitment to extending healthspan through rigorous research drives us to explore innovative, clinically-backed ways to support health and longevity. At the core of Prolon products lies the science of Fasting Mimicking Nutrition Technology—a breakthrough designed to deliver the extensive health benefits of fasting, while still nourishing the body with scientifically formulated foods.
Developed over 25 years in collaboration with the Longevity Institute at the University of Southern California and L-Nutra Inc., Prolon's 5-Day Fasting Mimicking Diet (FMD) has transformed fasting into a scientifically-backed, food-based approach to longevity.
This clean, plant-based nutrition protocol supports the body's metabolism and cells in fasting mode, tapping into autophagy and enabling cellular rejuvenation. With $48 million in funding and rigorous testing through 47 clinical trials at 18 globally renowned institutions — including Stanford, Mayo Clinic, University of Miami, and University of Genoa, and more — Prolon’s Fasting Mimicking Nutrition has gained recognition for its contributions to the field of Food as Medicine.
Notably, these trials have shown that completing three to six cycles of the Prolon FMD each year can lead to profound health benefits, including reduced biological age score, fat-focused weight loss with muscle preservation, healthy metabolic markers, and more
Grounded in Rigorous Science
Prolon’s science is built upon five foundational pillars, as defined by Dr. Valter Longo, one of the world’s leading longevity experts:
Juventology
Research
Research
This study of youth begins with preclinical research in animal models to examine the potential of diet to extend longevity.
Epidemiological
Research
Research
By understanding disease risk factors within populations, we can further test and validate hypotheses arising from our research.
Clinical
Studies
Studies
Through randomized, controlled trials, we evaluate the effectiveness and safety of our strategies in human subjects.
Centenarian
Studies
Studies
Research with centenarians helps us assess the long-term benefits of fasting-based nutrition strategiesResearch with centenarians helps us assess the long-term benefits of fasting-based nutrition strategies.
Complex Systems
Analysis
Analysis
By modeling the intricate interactions between food, cellular damage, and aging, we aim to unravel the complex mechanisms of longevity and metabolic health.
Through these pillars and ongoing clinical trials, Prolon's Fasting Mimicking Technology remains at the forefront of the nutrition and longevity fields, illustrating how strategic fasting-based nutrition can support healthier, longer lives.
Most Read Articles & Studies
NATURE
Could You Live Longer and Healthier by Reducing Your Biological Age
The harsh truth? Aging is inevitable. The prospect of wrinkles, fading energy, and the gradual decline of physical and mental abilities is enough to make anyone wish for a pause button on the relentless ticking clock.
BLOG
ARTICLE
Explore a selection of scientific and medical publications on the FMD and Fasting Mimicking Technology below:
