At Prolon, science isn’t a tagline; it’s our DNA. Developed in collaboration with the Longevity Institute at USC and created by world-renowned longevity scientist Dr. Valter Longo, Prolon’s Fasting Mimicking Diet (FMD) has been validated through 25 years of research and 40+ clinical trials.
Supported by $48M in funding and validated by research with 18 leading institutions—including Stanford, Mayo Clinic, the University of Miami, and the University of Genoa—Prolon is the first and only patented nutrition program shown to support longevity through cellular renewal.
Founded by scientists and grounded in peer-reviewed evidence, Prolon brings biotech-grade rigor to everyday nutrition. It’s not a trend. It’s a proven intervention designed to help you live healthier, longer.
Most read articles and studies
Prolon is the first nutrition program clinically proven to trigger autophagy in humans
Landmark human trial finds the FMD enhances autophagy while improving metabolic health.
How protein may accelerate your aging — and what you can do about it
While high-protein diets are trending right now, decades of research show that too much protein, especially from certain sources, can actually accelerate aging and increase long-term health risks.
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Could you live longer and Healthier by reducing your biological age
The harsh truth? Aging is inevitable. The prospect of wrinkles, fading energy, and the gradual decline of physical and mental abilities is enough to make anyone wish for a pause button on the relentless ticking clock.
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Explore the research
With more than 40 clinical trials published in leading scientific and medical journals worldwide, Prolon’s impact is proven by some of the most rigorous nutrition research to date. Browse a selection of our studies below.
