WEIGHT and METABOLIC WELLNESS PROGRAM
Personalized nutrition and hands-on coaching
Weight loss that lasts
One-on-one support and accountability
Quarterly bloodwork to track results
Control of your health — finally
Break free from endless dieting and forever meds with a sustainable program built on 25+ years of longevity science.
Weight / fat loss
Lose fat, protect muscle, and reset your relationship with food—without drugs or extreme dieting.
Blood lipids / cholesterol
Lower LDL cholesterol and triglycerides naturally—without lifelong medication.
Blood sugar
Support balanced blood sugar and improve insulin resistance.
Blood pressure
Lower blood pressure and ease the strain on your heart through science-backed nutrition, not drugs.
Powered by science. Delivered with care.
Transformation takes more than willpower. We combine rigorous research nutrition protocols and expert guidance
into a personalized plan to create healthier habits—and results—that stick.
Targeted nutrition
A monthly subscription to the patented Fasting Mimicking Diet. Replace guesswork with results—fat loss, muscle protection, and metabolic reset.
Personalized 1-on-1 coaching
Get two monthly 1-on-1 sessions with a longevity-science trained, dedicated dietitian who designs a plan for your health history, lifestyle, and goals.
Bloodwork + results tracking
Track your progress with quarterly lab testing.
Ongoing support
Stay accountable and motivated with guidance and continuous check-ins to keep you on track.
GET STARTED
Prolon’s Weight and Metabolic Wellness Program
Starting at
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Limited time 15% off month one,
plus get your second month free
Transform your health and go beyond the 5-Day with our most comprehensive program yet. Over 4–6 months, you’ll work one-on-one with a expert longevity dietitian who will guide you every step of the way—helping you lose weight, improve metabolic health, and create habits that last.
plus get your second month free
Select your Prolon kit:
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What's included
Personalized guidance every
month, to help you achieve your cardiometabolic goals
Monthly Prolon Nutrition Kit
You can swap kits anytime
Two one-on-one health coaching calls with a
registered longevity dietitian each month
Quarterly bloodwork panel and diagnosis
Free premium Prolon membership
Unlocks 20% off all Prolon products, and access
to exclusive offers
Biomarker scale to track progress
Welcome nutrition kit in the first month
More than promises—outcomes you can see, feel, and measure
Decades of research and guided care mean real results.
22lbs
Average fat-focused weight loss while preserving muscle.
67%
Reduction or elimination of medication reliance.
2.5yrs
Reduction in biological age score and improved markers.
10k
Cost savings from decrease in drug reliance.
By targeting the root causes of
ill-health, and activating your
body’s own ability to heal,
lasting change is possible.
ill-health, and activating your
body’s own ability to heal,
lasting change is possible.
Treat the root cause of weight and metabolic imbalance
Target fat, protects muscle
Doesn’t require a permanent, drastic lifestyle shift
Reduce medicine reliance over time
Reduce lifetime healthcare expense
Sustainable weight loss—without drugs
GLP-1 medications can offer weight loss, but they can come with trade offs: injections, high costs, muscle loss, and long term dependency.
OUR PROGRAM
GLP-1 MEDICATIONS
Fat / muscle loss
Fat loss and muscle protection: Lose dangerous visceral fat - while protecting precious muscle.
Muscle loss: Up to 40% of weight lost with GLP-1s can be lean muscle, not fat. That can slow your metabolism and make weight regain easier.
Cost
Cost-effective: Programs start at $199, a fraction of what drugs can cost.
Costly commitment: Weekly injections add up, both financially and as a lifelong dependency.
Side effects
Drug-free, safe: The program works with your body's natural processes, not against them. No drugs, no side effects
Side effects: From nausea to more serious risks, GLP-1s may take a toll.
Sustainability
Sustainable results: The program resets your metabolism and relationship with food, for lasting results. Studies show that weight loss from our program stays off, even after returning to a normal diet.
No clear exit plan: Stopping GLP-1s often leads to weight regain, leaving you stuck in a cycle.
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Cardiometabolic health is the backbone of good health, influencing how your body ages and how you feel day to day.
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Recommended by thousands of
healthcare professionals
Prolon’s 5-Day Program helps you lose visceral fat, while you preserve lean muscle mass. It’s flexible, it’s convenient, and—most importantly—it’s scientifically proven, safe, and it works. And with Prolon, you’re not just losing that fat, you’re resetting your relationship with food.
Dr. Beverly Yates
MD Scientific Advisor“I love the science supporting Prolon, and I love that the science has been published in multiple peer hyphen reviewed journals. It allows me to recommend Prolon with confidence. I have used fasting and time-restricted eating in my practice for years; Prolon augments this and takes it to the next level.”
Dr. Joel Kahn
MD, cardiologistProlon is my first choice for patients looking for a simple and effective way to lose body fat, while protecting their precious muscle mass and feel better overall. Cellular rejuvenation is the key to staying youthful and Prolon makes it easy.
Dr. Robert Lufkin
MD Scientific AdvisorFAQs
We created the program because we know how frustrating it can be to put in all the work and have all the willpower in the world and not meet your health goals.
The Metabolic Reset Program provides complete, science-backed care for lasting weight loss and improved cardiometabolic health. It combines nutrition technology with expert, personalized guidance—so you’re not left guessing at how to get results, and you’re not left on your own.
Grounded in 25+ years of research and 47+ clinical trials, the program builds on the patented science behind the Prolon Fasting Mimicking Diet (FMD)—a clinically proven protocol that gives your body the benefits of fasting while still providing nourishment. It’s the best of both worlds: rigorous science you can trust, and expert human support to make it work for you.
The Metabolic Reset Program provides complete, science-backed care for lasting weight loss and improved cardiometabolic health. It combines nutrition technology with expert, personalized guidance—so you’re not left guessing at how to get results, and you’re not left on your own.
Grounded in 25+ years of research and 47+ clinical trials, the program builds on the patented science behind the Prolon Fasting Mimicking Diet (FMD)—a clinically proven protocol that gives your body the benefits of fasting while still providing nourishment. It’s the best of both worlds: rigorous science you can trust, and expert human support to make it work for you.
Nutrition technology— The program is centered on a structured, science-backed nutrition plan based on the patented Fasting Mimicking Diet. The FMD is the only nutrition protocol proven to trigger cellular renewal while nourishing your body, delivering measurable results without the guesswork.
Personalized 1-on-1 coaching— Work directly with a longevity-trained, registered dietitian who tailors your plan to your lifestyle and goals, and supports you every step of the way.
Bloodwork + results tracking— Lab testing, including Complete Blood Count (CBC) and Comprehensive Metabolic Panel (CMP), reviewed quarterly to track progress and ensure measurable improvements.
Ongoing support— Stay accountable and motivated with guidance and continuous check-ins to keep you on track. You’ll have two 1-1 sessions with a dietitian for progress tracking, and coaching on lifestyle factors like exercise, stress, sleep, and daily nutrition— so you’re set up for success during, and after, the program.
Personalized 1-on-1 coaching— Work directly with a longevity-trained, registered dietitian who tailors your plan to your lifestyle and goals, and supports you every step of the way.
Bloodwork + results tracking— Lab testing, including Complete Blood Count (CBC) and Comprehensive Metabolic Panel (CMP), reviewed quarterly to track progress and ensure measurable improvements.
Ongoing support— Stay accountable and motivated with guidance and continuous check-ins to keep you on track. You’ll have two 1-1 sessions with a dietitian for progress tracking, and coaching on lifestyle factors like exercise, stress, sleep, and daily nutrition— so you’re set up for success during, and after, the program.
If you’ve struggled to get your weight or health on track, tried wellness protocols that didn’t work, or simply want a reset and results that stick, this program is designed for you.
It’s especially effective if you’re dealing with:
Weight challenges—if you’re overweight or want sustainable fat loss while protecting muscle.
Metabolic imbalance—if markers like LDL cholesterol, triglycerides, blood pressure, or insulin resistance are outside the ideal range.
Cardiometabolic conditions— if you’re dealing with challenges such as hypertension, high cholesterol, hyperlipidemia, prediabetes, or inflammation.
Medication reliance—if you’re currently using medications for blood pressure, cholesterol, or weight loss (including GLP-1s) and want to optimize your health, or plan a path forward after stopping.
Low energy or poor health—if you simply don’t feel as well as you’d like and want expert guidance on sustainable change.
Note: If you’ve been diagnosed with type 2 diabetes, or are currently taking insulin or diabetes medications, our Diabetes Remission & Regression Program will be a better fit for your needs.
It’s especially effective if you’re dealing with:
Weight challenges—if you’re overweight or want sustainable fat loss while protecting muscle.
Metabolic imbalance—if markers like LDL cholesterol, triglycerides, blood pressure, or insulin resistance are outside the ideal range.
Cardiometabolic conditions— if you’re dealing with challenges such as hypertension, high cholesterol, hyperlipidemia, prediabetes, or inflammation.
Medication reliance—if you’re currently using medications for blood pressure, cholesterol, or weight loss (including GLP-1s) and want to optimize your health, or plan a path forward after stopping.
Low energy or poor health—if you simply don’t feel as well as you’d like and want expert guidance on sustainable change.
Note: If you’ve been diagnosed with type 2 diabetes, or are currently taking insulin or diabetes medications, our Diabetes Remission & Regression Program will be a better fit for your needs.
No. The program is a great fit whether you have an existing health issue like hypertension, prediabetes, or obesity, or are simply looking to lose weight and restore your metabolic balance and overall health.
The Metabolic Reset Program is designed to deliver measurable, sustainable improvements in both weight and cardiometabolic health. Results vary by individual, but the plan provides real help with some of the most common health issues and goals including:
Weight loss
Target visceral fat—the type of fat most dangerous to your health—while protecting lean muscle. Many participants also report improved satiety and a healthier relationship with food.
Blood lipids
Lower LDL cholesterol and triglycerides naturally, while supporting healthier HDL levels—reducing reliance on medication for many.
Blood sugar
Improve insulin sensitivity, balance blood sugar, and lower your risk for prediabetes and type 2 diabetes.
Blood pressure
Reduce blood pressure and ease strain on the heart through a nutrition-first, drug-free approach.
Over time, these improvements compound—supporting healthier aging, reducing lifetime healthcare costs, and helping you feel more energized, resilient, and in control.
Weight loss
Target visceral fat—the type of fat most dangerous to your health—while protecting lean muscle. Many participants also report improved satiety and a healthier relationship with food.
Blood lipids
Lower LDL cholesterol and triglycerides naturally, while supporting healthier HDL levels—reducing reliance on medication for many.
Blood sugar
Improve insulin sensitivity, balance blood sugar, and lower your risk for prediabetes and type 2 diabetes.
Blood pressure
Reduce blood pressure and ease strain on the heart through a nutrition-first, drug-free approach.
Over time, these improvements compound—supporting healthier aging, reducing lifetime healthcare costs, and helping you feel more energized, resilient, and in control.
During your first month in the Prolon Metabolic Reset Program, you’ll complete a set of baseline lab tests that provide insight into your heart and metabolic health. These results give us a clear starting point and allow our dietitians to tailor your program for the best possible outcomes.Here’s what we measure:
Complete Blood Count (CBC): Evaluates your red blood cells, white blood cells, platelets, and triglycerides. This helps us understand oxygen-carrying capacity, immune function, cholesterol balance, and overall blood health.
Comprehensive Metabolic Panel (CMP): Looks at kidney and liver health, blood sugar, protein levels, and electrolytes - important markers of how your body is functioning at a cellular level.
Ongoing tracking: Your labs aren’t just a one-time check. After your initial month, we repeat these labs every three months for the duration of your program. This allows us to measure your progress, make adjustments along the way, and ensure your nutrition plan continues to support fat-focused weight loss, muscle protection, and long-term metabolic balance. (edited)
Complete Blood Count (CBC): Evaluates your red blood cells, white blood cells, platelets, and triglycerides. This helps us understand oxygen-carrying capacity, immune function, cholesterol balance, and overall blood health.
Comprehensive Metabolic Panel (CMP): Looks at kidney and liver health, blood sugar, protein levels, and electrolytes - important markers of how your body is functioning at a cellular level.
Ongoing tracking: Your labs aren’t just a one-time check. After your initial month, we repeat these labs every three months for the duration of your program. This allows us to measure your progress, make adjustments along the way, and ensure your nutrition plan continues to support fat-focused weight loss, muscle protection, and long-term metabolic balance. (edited)
Diets focus on short-term restriction, and drugs focus on symptom management. The Metabolic Reset Program is different: it works with your body’s natural processes to create lasting change.
Activating your body’s own ability to heal.
Science-backed
Built on 25+ years of longevity and nutrition research, the program uses the patented Prolon Fasting Mimicking Diet (FMD) to trigger cellular renewal and target visceral fat while protecting muscle mass. No guesswork, no gimmicks—just proven results.
Muscle protection vs. muscle loss
GLP-1 drugs (like Wegovy or Zepbound) can deliver weight loss, but studies show up to 40% of that loss may come from muscle, slowing your metabolism and making it harder to keep the weight off. Prolon’s nutrition technology helps you lose fat while protecting your strength.
Drug-free, side-effect-free
Unlike injections that can cost $350–$500 per month, may come with serious side effects, and may require ongoing use to maintain results, Prolon is drug-free. The program activates your body’s own ability to heal, and delivers sustainable results. No needles, no nausea, no long-term dependency.
High tech + high touch
The program pairs rigorous science with expert, 1-on-1 dietitian support and lab tracking, so you’re supported as you progress toward your goal. That combination of evidence and personal guidance is what makes the results both real and sustainable.
In short: it’s not another crash diet or costly injection. It’s a clinically proven way to reset your metabolism, lose weight safely, and improve the health markers that matter most—without trading one problem for another.
Activating your body’s own ability to heal.
Science-backed
Built on 25+ years of longevity and nutrition research, the program uses the patented Prolon Fasting Mimicking Diet (FMD) to trigger cellular renewal and target visceral fat while protecting muscle mass. No guesswork, no gimmicks—just proven results.
Muscle protection vs. muscle loss
GLP-1 drugs (like Wegovy or Zepbound) can deliver weight loss, but studies show up to 40% of that loss may come from muscle, slowing your metabolism and making it harder to keep the weight off. Prolon’s nutrition technology helps you lose fat while protecting your strength.
Drug-free, side-effect-free
Unlike injections that can cost $350–$500 per month, may come with serious side effects, and may require ongoing use to maintain results, Prolon is drug-free. The program activates your body’s own ability to heal, and delivers sustainable results. No needles, no nausea, no long-term dependency.
High tech + high touch
The program pairs rigorous science with expert, 1-on-1 dietitian support and lab tracking, so you’re supported as you progress toward your goal. That combination of evidence and personal guidance is what makes the results both real and sustainable.
In short: it’s not another crash diet or costly injection. It’s a clinically proven way to reset your metabolism, lose weight safely, and improve the health markers that matter most—without trading one problem for another.