Helping you feel better now, and live better longer
We applied 25 years of longevity science to simple, proven programs that help people live better, longer.
Collectively, we are spending more on healthcare. But we’re not getting healthier. It’s one of the critical problems of our time, and one that Prolon was created to help solve.
Prolon is the flagship brand of L-Nutra, offering a holistic platform of products focused on reversing aging and unlocking better health. L-Nutra was born in 2009 with a vision rooted in decades of scientific inquiry.
The company was founded by Dr. Valter Longo, Director of the Longevity Institute at USC and the Longevity and Cancer Program at IFOM Milan, author of international bestseller, The Longevity Diet, and a global leader in nutrition and longevity science.
Dr. Longo has spent decades studying the world's longest-lived people, the mechanisms of aging, and the role of nutrition in health, and his research laid the foundation for Prolon’s products and programs. We are driven by a mission to extend human healthspan. We do this by translating nutrition science into practical, impactful products and programs that help people feel better and thrive for longer.
Our company and products were built on peer-reviewed research, and driven by the same rigor you’d expect from biotech or medicine. We have 25+ years of clinical research backing our products, and 40+ scientific studies that we have conducted and published in association with the world’s leading institutions including USS, Mayo Clinic, and Stanford. We encourage you to compare that scientific track record to any other wellness product (or any product) you may use.
That commitment to scientific proof means you can use Prolon with confidence—knowing it’s not just another wellness product or trend, but a program rooted in real science, proven results, and a mission to help you live healthier, longe
Our difference
Natural solutions, whole-health benefits: Our products and programs work with your body, tapping into its innate ability to heal.
Biotech-level scientific rigor: 25+ years of peer-reviewed research, 40+ clinical trials, 18 top-tier university research partners.
Expert support: We offer 1-on-1 coaching and structured programs.
Trusted worldwide: 1 million users, recommended by thousands of healthcare professionals.
Our Mission
Our mission is to extend human healthspan through science-backed nutrition programs that reset the body and rejuvenate health—from within.
A timeline of innovation
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2025
New research shows conclusively that the Prolon FMD triggers autophagy in humans.
2024
Three consecutive cycles of the FMD are shown to decrease biological age by an average of 2.5 years, reduce liver fat, support immune profile, and healthy metabolic markers.
2023
The FMD is shown to increase skin hydration, even skin tone, and preserve smoothness, boost self-perceived radiance and confidence.
20 days of the FMD is shown to deliver heart health benefits equivalent to 120 days of the Mediterranean Diet, and was found to be superior in promoting sustained weight loss, greater visceral fat reduction, and better preservation of lean muscle mass.
2022
The FMD demonstrates improvements in neuromuscular function.
L-Nutra's medical division is founded.
2021
Clinical trial results from diabetic patient populations reveal that the low-glycemic FMD can help reduce A1C, body weight, and medication use.
2020
Prolon launches new products including Fasting Bars and the Fasting Shake, to support intermittent fasting and to make it easier to eat for longevity every day.
2017
The FMD is shown to mitigate markers and risk factors for aging, diabetes, cancer, cardiovascular disease, and other ailments.
2016
Prolon is launched as the first and only Fasting Mimicking Diet, making the benefits of fasting available to everyone.
2015
Peer-reviewed studies show The Fasting Mimicking Diet promotes multi-system regeneration, enhanced cognitive performance, and healthspan..
Study shows higher animal protein intake linked to increased cardiovascular mortality. Higher plant protein—as recommended in the Longevity Diet—is linked to lower all-cause and heart-related mortality.
2009
Dr. Longo starts L-Nutra, the parent company of Prolon. He creates the Fasting Mimicking Diet, a 5-day nutrition program that allows people to get the benefits of fasting, while still eating food.
2001
Dr. Longo’s yeast research is published and embraced, kicking off more research into nutrition and fasting and its influence on how organisms age.
1994
Dr. Valter Longo pioneers longevity research with the first study on the impact of food on the rate of aging in yeast. The paper was rejected by journals.
Scientific authority and clinical expertise
Leaders in bringing longevity science to life
Valter Longo, PhD
Founder of L-Nutra
Director of the USC Longevity Institute, inventor of the Fasting Mimicking Diet, and author of The Longevity Diet. A world-renowned pioneer in nutrition and aging research who has studied longevity for over 30 years.
Joseph Antoun, MD, PhD, MPP
Chief Executive Officer
A physician and public health expert focused on transforming healthcare from prescription-based to food-based care.
William Hsu, MD
Chief Medical Officer
Harvard-trained endocrinologist and former VP at Joslin Diabetes Center. Leads clinical program development and care protocols.
Shaping the dialogue on health and aging
We’re proud to be part of the global conversation on health, nutrition, and longevity.
Discover the science
Prolon is the only nutrition program patented for supporting longevity, healthspan, and protecting lean body mass through cellular rejuvenation.