Fuel your fast. Power your movement.

Your 5-Day Prolon reset in motion. Enjoy our partnership with ClassPass — for a limited time receive a free one-month membership, plus 50 bonus credits with your Prolon 5-Day purchase.

Prolon + ClassPass

FEATURED IN

Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo
Partner logo

#1 Doctor Recommended Fasting Mimicking Diet (FMD) — Prolon

Thepower of fasting with food.Prolon 5-Day is a patented and scientifically-backed Fasting Mimicking Diet (FMD) that activates cellular clean-up pathways while allowing you to eat.

Over five days, you receive precisely formulated meals that help your body enter a rejuvenating state called autophagy.

This program helps you clear out cellular waste, lose weight while protecting your muscle mass, and support your overall health while still nourishing your body.

Prolon 5-Day

Provider discount appliedat checkout

($205/box)

($146/box)

  • Checkmark

    Five Days to Cellular Rejuvenation

    A physical and mental reset backed by 25 years of clinical research and science to rejuvenate at the cellular level.

  • Checkmark

    Lose Fat and Protect Muscle

    Fat-targeted weight loss while preserving muscle – results shown to be sustainable even after returning to regular eating.

  • Checkmark

    Science-Backed Fasting Made Easier

    Experience the benefits of fasting while still receiving nourishment, the revolution of fasting with food.

  • Checkmark

    Limited-time Free Fasting Bars

    Enjoy free Variety Pack Fasting Bars when you subscribe. Keep your health goals going between cycles of Prolon.

Access the Lowest Prices Through Your Provider

—Now with Subscriptions!

START NOW

Recommended by thousands of
healthcare professionals

Prolon’s 5-Day Program helps you lose visceral fat, while you preserve lean muscle mass. It’s flexible, it’s convenient, and—most importantly—it’s scientifically proven, safe, and it works. And with Prolon, you’re not just losing that fat, you’re resetting your relationship with food.

Dr. Beverly Yates

MD Scientific Advisor

I love the science supporting Prolon, and I love that the science has been published in multiple peer hyphen reviewed journals. It allows me to recommend Prolon with confidence. I have used fasting and time-restricted eating in my practice for years; Prolon augments this and takes it to the  next level.”

Dr. Joel Kahn

MD, cardiologist

Prolon is my first choice for patients looking for a simple and effective way to lose body fat, while protecting their precious muscle mass and feel better overall. Cellular rejuvenation is the key to staying youthful and Prolon makes it easy.

Dr. Robert Lufkin

MD Scientific Advisor
Prolon is the only nutrition program patented for promoting longevity, healthspan, and protecting lean body mass through cellular rejuvenation.

From the pioneers in longevity science

Prolon is the only nutrition program patented for supporting longevity, healthspan, and protecting lean body mass through cellular rejuvenation.

25+

Years of scientific research

Research developed in partnership with top institutions.

47

Clinical trials

Conducted and published in association with the world’s leading institutions.

18

Leading research institutions

Including Stanford, Mayo Clinic, and more.

200+

Pending or issued patents

To support research and development.

1M+ Happy Healthy Customers

Backed by science, loved by users

Video thumbnail

“It works—weight management, energy, and mental clarity.”

- Zaree

Verified Reviewer

Video thumbnail

"I lost 5 pounds my first round and felt amazing."

- Amy

Verified Reviewer

FAQs

We created the program because we know how frustrating it can be to put in all the work and have all the willpower in the world and not meet your health goals.

The Metabolic Reset Program provides complete, science-backed care for lasting weight loss and improved cardiometabolic health. It combines nutrition technology with expert, personalized guidance—so you’re not left guessing at how to get results, and you’re not left on your own.

Grounded in 25+ years of research and 47+ clinical trials, the program builds on the patented science behind the Prolon Fasting Mimicking Diet (FMD)—a clinically proven protocol that gives your body the benefits of fasting while still providing nourishment. It’s the best of both worlds: rigorous science you can trust, and expert human support to make it work for you.
Nutrition technology— The program is centered on a structured, science-backed nutrition plan based on the patented Fasting Mimicking Diet. The FMD is the only nutrition protocol proven to trigger cellular renewal while nourishing your body, delivering measurable results without the guesswork.

Personalized 1-on-1 coaching— Work directly with a longevity-trained, registered dietitian who tailors your plan to your lifestyle and goals, and supports you every step of the way.

Bloodwork + results tracking— Lab testing, including Complete Blood Count (CBC) and Comprehensive Metabolic Panel (CMP), reviewed quarterly to track progress and ensure measurable improvements.

Ongoing support— Stay accountable and motivated with guidance and continuous check-ins to keep you on track. You’ll have two 1-1 sessions with a dietitian for progress tracking, and coaching on lifestyle factors like exercise, stress, sleep, and daily nutrition— so you’re set up for success during, and after, the program.
If you’ve struggled to get your weight or health on track, tried wellness protocols that didn’t work, or simply want a reset and results that stick, this program is designed for you.

It’s especially effective if you’re dealing with:

Weight challenges—if you’re overweight or want sustainable fat loss while protecting muscle.

Metabolic imbalance—if markers like LDL cholesterol, triglycerides, blood pressure, or insulin resistance are outside the ideal range.

Cardiometabolic conditions— if you’re dealing with challenges such as hypertension, high cholesterol, hyperlipidemia, prediabetes, or inflammation.

Medication reliance—if you’re currently using medications for blood pressure, cholesterol, or weight loss (including GLP-1s) and want to optimize your health, or plan a path forward after stopping.

Low energy or poor health—if you simply don’t feel as well as you’d like and want expert guidance on sustainable change.

Note: If you’ve been diagnosed with type 2 diabetes, or are currently taking insulin or diabetes medications, our Diabetes Remission & Regression Program will be a better fit for your needs.
No. The program is a great fit whether you have an existing health issue like hypertension, prediabetes, or obesity, or are simply looking to lose weight and restore your metabolic balance and overall health.
The Metabolic Reset Program is designed to deliver measurable, sustainable improvements in both weight and cardiometabolic health. Results vary by individual, but the plan provides real help with some of the most common health issues and goals including:

Weight loss

Target visceral fat—the type of fat most dangerous to your health—while protecting lean muscle. Many participants also report improved satiety and a healthier relationship with food.

Blood lipids

Lower LDL cholesterol and triglycerides naturally, while supporting healthier HDL levels—reducing reliance on medication for many.

Blood sugar

Improve insulin sensitivity, balance blood sugar, and lower your risk for prediabetes and type 2 diabetes.

Blood pressure

Reduce blood pressure and ease strain on the heart through a nutrition-first, drug-free approach.

Over time, these improvements compound—supporting healthier aging, reducing lifetime healthcare costs, and helping you feel more energized, resilient, and in control.
During your first month in the Prolon Metabolic Reset Program, you’ll complete a set of baseline lab tests that provide insight into your heart and metabolic health. These results give us a clear starting point and allow our dietitians to tailor your program for the best possible outcomes.Here’s what we measure:

Complete Blood Count (CBC): Evaluates your red blood cells, white blood cells, platelets, and triglycerides. This helps us understand oxygen-carrying capacity, immune function, cholesterol balance, and overall blood health.

Comprehensive Metabolic Panel (CMP): Looks at kidney and liver health, blood sugar, protein levels, and electrolytes - important markers of how your body is functioning at a cellular level.

Ongoing tracking: Your labs aren’t just a one-time check. After your initial month, we repeat these labs every three months for the duration of your program. This allows us to measure your progress, make adjustments along the way, and ensure your nutrition plan continues to support fat-focused weight loss, muscle protection, and long-term metabolic balance. (edited)
Diets focus on short-term restriction, and drugs focus on symptom management. The Metabolic Reset Program is different: it works with your body’s natural processes to create lasting change.

Activating your body’s own ability to heal.

Science-backed

Built on 25+ years of longevity and nutrition research, the program uses the patented Prolon Fasting Mimicking Diet (FMD) to trigger cellular renewal and target visceral fat while protecting muscle mass. No guesswork, no gimmicks—just proven results.

Muscle protection vs. muscle loss

GLP-1 drugs (like Wegovy or Zepbound) can deliver weight loss, but studies show up to 40% of that loss may come from muscle, slowing your metabolism and making it harder to keep the weight off. Prolon’s nutrition technology helps you lose fat while protecting your strength.

Drug-free, side-effect-free

Unlike injections that can cost $350–$500 per month, may come with serious side effects, and may require ongoing use to maintain results, Prolon is drug-free. The program activates your body’s own ability to heal, and delivers sustainable results. No needles, no nausea, no long-term dependency.

High tech + high touch

The program pairs rigorous science with expert, 1-on-1 dietitian support and lab tracking, so you’re supported as you progress toward your goal. That combination of evidence and personal guidance is what makes the results both real and sustainable.

In short: it’s not another crash diet or costly injection. It’s a clinically proven way to reset your metabolism, lose weight safely, and improve the health markers that matter most—without trading one problem for another.