The Longevity Program
Starting at $99.00/month
Your Longevity Dietitian, your labs, your results. The Longevity Program pairs you with a registered dietitian who designs your plan around your own biomarkers, then stays with you month after month to refine it.
Talk to a Longevity Expert
Get answers and find the right program for you.
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The Longevity Program isn't available in New York, New Jersey or Rhode Island at this time. Manage or cancel your membership anytime from Account > Program in the app.
40+
human clinical
trials
42
international research
collaborations
150
issued
patents
25+
years of longevity
research9
Peer-reviewed and published in
The experts behind your plan
A Longevity Dietitian team you can call your own.
A Longevity Dietitian who knows you by name, and a practitioner-led team of longevity experts behind them.
Trained in the Longevity Diet method, your Longevity Dietitian knows your labs and your goals. They plan and track your progress, and are a message away whenever you need them.
Our Longevity Dietitians and physicians are the same clinical team behind L-Nutra Health's physician-supervised programs.
Your Longevity Dietitian
A private session every month, and a direct line in between.
Dr. William Hsu, MD
Chief Medical Officer. Leads clinical care.
Ashley Bizzell, RD, CDCES
Director of Clinical Nutrition and Global Training. Designs member protocols.
Your labs, explained
Baseline and follow-up labs are always included, and your dedicated dietitian walks you through every result and what to do next.
How it works
How your membership works, step by step.
1
Meet.
Your Longevity Dietitian learns your goals, your history, and your week.
2
Measure.
Labs at a Labcorp near you, included, plus your Apple Health data.
3
Move.
Your Longevity Dietitian builds a plan around your biology, with targeted interventions.
4
Track.
Follow-up labs show what changed. When they call for more, clinical care steps in.
How it compares
One-on-one longevity care, without the $12,000 price tag.
Others measure how you're aging. Our experts help you change it.
Hospital longevity programs
Lab-testing memberships
Dietitian visits through insurance
Prolon Longevity Program
Your own Longevity Dietitian
Varies
No
Varies
Yes
Labs, reviewed with you
Yes
Results only
No
Yes
Clinically tested protocol1, 5
No
No
No
Yes
Physician care when needed
Yes
No
Varies
Yes
Price
$5,500 to $12,000/yr4
$199 to $365/yr
Varies by plan
From $99/mo
Members-only learning
A year of longevity, one focus a month.
Each month, a renowned longevity expert goes live on one of the six pillars of longevity: nutrition and fasting, movement, sleep, stress, connection, and environment. Your Longevity Dietitian helps you put it into practice.
- Nutrition and fasting
- Movement
- Sleep
- Stress
- Connection
- Environment
Clinically backed precision nutrition
Targeted interventions, timed to your biology.
Your plan runs on the principles of the Longevity Diet. Want to go further? Add the 5-Day FMD Protocol three times a year with our Guided + Protocol membership: five days of plant-based nutrition backed by 41 published studies that triggers autophagy.7 Other Prolon products come at member pricing.
The 5-Day FMD Protocol, in clinical studies
5.7 lbs
clinically proven average weight loss after three consecutive monthly rounds5
Lean muscle protected
protects lean muscle mass while reducing visceral fat5
About 2.5 years
median reduction in biological age after three monthly cycles, in a clinical study of healthy adults9
25%
improvement in fine lines, skin tone, texture, and hydration after three consecutive monthly cycles6
Energy and focus
reported by users after the fast8
Our science team
Built by real practitioners.
-
Chief Medical Officer
Dr. William Hsu, MD
Harvard-trained endocrinologist and former VP at Joslin Diabetes Center. Leads clinical program development and care protocols.
-
Director of Clinical Nutrition and Global Training
Ashley Bizzell, RD, LDN, CDCES
Registered Dietitian specializing in metabolic health and longevity-informed nutrition. Heads member protocol design.
-
Chief Executive Officer
Dr. Joseph Antoun, MD, PhD, MPP
A physician and public health leader driving the science and strategy behind the Longevity Program.
When your labs call for more
Our clinical programs: physician-supervised care, guided by your labs and progress.
For type 2 diabetes or cardiometabolic risk: your Longevity Dietitian twice a month and 5-Day FMD cycles. Diabetes Care adds telehealth visits with Lifestyle Medicine physicians, with physician-led supervision. Cardiometabolic Care keeps your primary care physician updated. Alongside your usual care, never instead of it.
The clinical results behind these programs
53% vs 8%
improved glycemic management with monthly FMD cycles plus usual care, vs usual care alone, in a 12-month randomized trial1
8.1% → 6.7%
average HbA1c after six monthly cycles, in a 6-month randomized pilot2
−4.1 mmHg
average drop in systolic blood pressure (−2.3 mmHg diastolic), across 11 randomized trials3
Your guided longevity plan, in your pocket.
Message your Longevity Dietitian, book sessions, and sync Apple Health. Quick question at midnight? Just ask Prolon AI, trained by our Longevity Dietitians, anytime.
Built for anyone who is ready to live a longer and healthier life.
- Your own Longevity Dietitian, a message away
- Baseline and follow-up labs, explained to you
- Nutrition protocols built on 25+ years of research
- Monthly live sessions with leading longevity experts
If you're ready to invest in how you age, we're ready for you.
Join the ProgramQuestions, answered.
What is the Prolon Longevity Program?
A longevity membership built around one relationship: your Longevity Dietitian, with physicians and renowned longevity experts behind them. Your plan starts with your own labs and builds on 25+ years of leading longevity research.
What happens after I join?
You're paired with your Longevity Dietitian, a registered dietitian trained in the Longevity Diet who stays with you through your membership. You start with a 45-minute session and baseline labs at a Labcorp near you, and build your plan together. After that, each month brings a private 30-minute session and a live session with a renowned longevity expert. In between, message your Longevity Dietitian for a reply within 24 hours, or ask Prolon AI in the app anytime.
What's the difference between Guided and Guided + Protocol?
Guided gives you your Longevity Dietitian, your labs, and a plan built with you. Guided + Protocol adds the 5-Day FMD Protocol about three times a year: five days of plant-based food, so you eat throughout. When your box arrives, hold off until you've met your Longevity Dietitian, who'll help you pick a start date.
Do I need blood work?
Yes, and it's included in both Guided and Guided + Protocol. You start with a baseline panel at a Labcorp near you, covering a metabolic panel, a lipid panel, and IGF-1, then get follow-up labs to see what's changed. Your Longevity Dietitian walks you through every result.
I've done the Prolon 5-Day before. What's different here?
You already know the five days. The membership is about everything around them: labs that show where you're starting, a Longevity Dietitian who plans the weeks in between with you, and monthly expert sessions on sleep, movement, stress, and more.
Can my plan fit how I eat?
Yes. Your Longevity Dietitian builds your meal plan around you, whether you eat vegan, vegetarian, gluten-free, or something else, and makes sure you're getting enough protein. After each 5-Day FMD Protocol, they'll help you ease back into eating, too.
How does the app fit in?
The Prolon Longevity Program app is home base: your plan, sessions, messages, and reminders all live there, so turn on notifications when you set it up. Connect Apple Health and your Longevity Dietitian sees your sleep and activity data.
How is this different from a dietitian through my insurance?
Insurance-covered dietitians usually focus on treating one condition. Your Longevity Dietitian plans for the long run, with labs included, a clinically tested nutrition protocol¹ ⁵, and monthly expert sessions.
Are there side effects?
In clinical studies, side effects were generally mild and temporary, such as weakness or headache on fasting days.² ⁵ If you take glucose-lowering medication, your care team guides any adjustments.
How do the clinical programs work?
If your labs indicate type 2 diabetes or cardiometabolic risk, your Longevity Dietitian may recommend a clinical program based on your labs, health history, and program criteria. A physician then reviews your results and makes any diagnosis. Eligibility is a clinical decision. Clinical programs complement your existing care; any medication changes are made by a physician.
Can I cancel or change tiers?
Yes. Manage, change, or cancel your membership anytime from Account > Program in the app, which opens your subscription settings. Your Longevity Dietitian or our support team can help. The signup fee is only charged once, so changing tiers won't add it again.
The Longevity Program Guided and Guided + Protocol tiers are wellness programs and do not diagnose or treat any disease. Diabetes Care is provided under physician supervision. Cardiometabolic Care is led by registered dietitians, in coordination with each member's primary care physician. Individual results vary. Study results describe trial participants, not guaranteed program outcomes. Patient stories are from L-Nutra Health clinical programs; results are not typical or guaranteed, and medication changes were made only by each patient's physician. Energy and focus are user-reported, after the fast. Pricing for hospital clinics per reference 4.
References
- van den Burg EL, et al. Integration of a fasting-mimicking diet programme in primary care for type 2 diabetes reduces the need for medication and improves glycaemic control: a 12-month randomised controlled trial. Diabetologia. 2024;67:1245-1259.
- Sulaj A, et al. Six-month periodic fasting in patients with type 2 diabetes and diabetic nephropathy: a proof-of-concept study. Journal of Clinical Endocrinology and Metabolism. 2022;107:2167-2181.
- Mohammadzadeh M, et al. Impact of fasting mimicking diet (FMD) on cardiovascular risk factors: a systematic review and meta-analysis of randomized control trials. Diabetology and Metabolic Syndrome. 2025;17:137.
- Zimmerman E. Is longevity medicine going mainstream? The New York Times. October 16, 2026.
- Wei M, et al. Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease. Science Translational Medicine. 2017;9:eaai8700.
- Maloh J, et al. The effects of a fasting mimicking diet on skin hydration, skin texture, and skin assessment. Journal of Clinical Medicine. 2023;12:1710.
- Espinoza SE, et al. Effect of fasting-mimicking diet on markers of autophagy and metabolic health in human subjects. GeroScience. 2025.
- Energy and focus are user-reported by Prolon customers after completing the fast; not a measured clinical outcome.
- Brandhorst S, et al. Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk. Nature Communications. 2024;15:1309.