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25% off sitewide
30% off over $250
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BLACK FRIDAY SAVINGS

25% off sitewide
30% off over $250
35% off over $350

Your journey, your way. The more you spend, the more you save on Prolon's fasting and longevity nutrition or join our 1-on-1 guided program— now is the time to save and invest in your health.

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Feel better now. Live better longer.

Work with your body’s biology to lose weight, transform your health, and build habits that last.

DEEP <br>RENEWAL <br> IN FIVE DAYS<br>

DEEP
RENEWAL
IN FIVE DAYS

Reset, rejuvenate, and lose fat in just five days with the patented Fasting Mimicking Diet.
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1-ON-1 <br> COACHING <br>PROGRAM

1-ON-1
COACHING
PROGRAM

Expert support for lasting weight loss and better metabolic health—without drugs or extreme diets.
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Reset your body, rejuvenate your cells—in five days

Reset your body, rejuvenate your cells—in five days


The most powerful changes come from within. That is the science-backed principle at the heart of Prolon.

The Prolon 5-Day Fasting Mimicking Diet is a patented and scientifically-backed program that activates cellular clean-up pathways while allowing you to eat.



Over five days, you’ll eat precisely formulated meals that help your body enter a rejuvenating state called autophagy.
This program helps you clear out cellular waste, lose weight while protecting muscle mass, and support your overall health while nourishing your body.

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Managing a metabolic condition? Join one of our personalized, medical nutrition programs for obesity, prediabetes or type 2 diabetes through L-Nutra Health — LEARN MORE


Find the program and product right for you

Trustpilot rating 4.1 out of 5 stars 4.1 stars 9,000+ reviews on Trustpilot
CORE PRODUCTS
Intermittent Fasting
Everyday Longevity
GUIDED PROGRAMS
Prolon 5-Day Program

REJUVENATION FROM WITHIN

Prolon 5-Day Program

Life-changing nutrition that rejuvenates cell and
metabolism while protecting lean body mass.
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Longevity Nutrition Kit

NUTRITION THAT WORKS

Longevity Nutrition Kit

Support longevity, weight management,
and cellular renewal with a flexible, science-
backed nutrition program—designed to fit
your lifestyle.
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Backed by decades of science

Backed by decades of science


Backed by over 25 years of research, Prolon is the first and only patented, clinically proven nutrition program designed to support longevity through cellular rejuvenation.

Proven in 37 clinical trials at 18 world-renowned institutions, Prolon brings cutting-edge nutrition innovation, and real health benefits, directly to you. Isn’t science beautiful?

DISCOVER THE SCIENCE

Prolon is the only nutrition program patented for supporting longevity, healthspan, and protecting lean body mass through cellular rejuvenation.

discover the science

Learn more about Prolon from longevity experts

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What is Prolon?




Joseph Antoun MD, PhD

CEO, Prolon

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Learn from a dietitian



Kristin Kirkpatrick

Dietitian, Cleveland Clinic

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Game changer for fasting



Sky C.

Olympic cyclist & entrepreneur

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Fasting is essential



Renee Fitton MS, RD

Director of Education, Prolon

SHOP PROLON PROLON BENEFITS
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DAY 01

Transition to a fasting state

The body transitions to a fasting state and fat-burning mode as it begins preparation for cellular clean-up.

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DAY 02

Fat burning begins

For most people, fat burning (ketosis) begins between 24–48 hours of their fast.

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DAY 03

Cellular clean-up begins

Autophagy, our body’s natural cellular clean-up system, ignites after 72 hours. Fat burning continues and increases.

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DAY 04

Rejuvenation in progress

Autophagy is fully activated, and cellular rejuvenation is in full effect.

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DAY 05

Cellular renewal peaks

On the last day of your fast, cellular renewal is at its peak, and you may experience an increase in energy.

REDUCE BIOAGE BY 2.5 YEARS

Defy aging by reversing your biological age


Three cycles of Prolon may decrease your bioage by 2.5 years in as few as 3 cycles over 3 months. Prolon 5-Day provides everything you need for a complete five day cellular rejuvenating fast, with food to nourish your body.

Don’t wait, start reversing your biological age today.

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Join the community and download our longevity diet guide for free

The Longevity Diet guide summarizes the main discoveries behind nutrition for longevity and food as medicine. Get your free copy now!