The Effects of a Fasting Mimicking Diet on Skin Hydration, Skin Texture, and Skin Assessment: A Randomized Controlled Trial
J Clin Med, 2023. Maloh J, et al.
Funding and competing interests (as published with the paper): J.M. serves as a consultant for Codex Labs. R.K.S. serves as a scientific advisor for LearnHealth, Arbonne, and Codex Labs and as a consultant to Burt’s Bees, Novozymes, Novartis, Bristol Myers Squibb, Nutrafol, Abbvie, Sanofi, Fotona, Incyte, Leo, UCB, Novartis, Biogena, Lilly, Sun, and Regeneron Pharmaceuticals. J.M., N.A. and R.K.S. were provided with the study data from L-Nutra for the analysis and for the writing of this manuscript. The authors, J.M., N.A. and R.K.S., are not consultants of L-Nutra and were not compensated for the writing of this manuscript. M.W., W.C.H. and S.C. are employees of L-Nutra.
- Study type
- Human clinical trial (randomized, n=45 women)
- Journal
- J Clin Med
- Published
- 2023
- Authors
- Maloh J, et al.
- DOI
- 10.3390/jcm12051710
- PubMed ID
- 36902498
Summary
Forty-five healthy women between 35 and 60 completed a randomized controlled trial testing a 5-day Fasting Mimicking Diet (FMD) protocol, given once a month for three months, measuring facial skin hydration, skin roughness, and self-reported mood over 71 days.
The authors reported a significant percentage increase in skin hydration at day 11 and at day 71 compared with baseline in the FMD group, and that skin texture was maintained in the FMD group while roughness increased in the control group. Participants also self-reported improvements in happiness and confidence.
This is a human trial, but a small one (45 women, ages 35 to 60), and three of the six study authors are employed by L-Nutra, Prolon's parent company. The mood and confidence results are self-reported, not a clinically diagnosed outcome.
A randomized trial in 45 healthy women aged 35 to 60. Three of the six authors are L-Nutra employees.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
