10 Reasons Men & Women Over 40 Are Choosing Prolon to Slow Aging
Dr. Joel Kahn, MD, FACC | Board Certified Cardiologist
Last Updated:
Still spending money on pills and creams that don't touch the real problem?
Works at
Results
Safety
Cellular level
Reduces biological age 2.5 yrs*
25 yrs research. Nobel Prize. 41+ trials.
NAD+/NMN Pills
Energy pathway only
Minimal measurable effect
A few animal studies
Anti-Aging Creams
Skin surface only
Temporary. Cosmetic
Who knows?
*Based on three consecutive monthly cycles.
Want to actually slow aging? Prolon’s 5-Day Fasting Mimicking Diet targets the real biological cause. Here is why. 👇
1. Reduce Your Biological Age By 2.5 Years
*Based on three consecutive monthly cycles.
A 2024 Nature Communications study found that three consecutive cycles of Prolon reduced biological age by a median of 2.5 years, measured using epigenetic clocks developed by Yale and USC.1
Just 15 days to reduce up to 2.5 years in your biological age.
*Based on three consecutive monthly cycles.
2. Unlocks Your Body's Own Nobel Prize-Winning Repair System
Your body has a built-in cellular cleanup system called autophagy, a discovery that earned the 2016 Nobel Prize in Physiology or Medicine.
The problem? Your normal eating habits almost never activate it.
In December 2025, a Cedars-Sinai clinical trial (the first ever on humans) confirmed Prolon activates measurable autophagy.2
No other nutrition program has proven this.
3. Clear The Belly Fat That Is Quietly Accelerating Your Aging
The fat that ages you fastest is hidden. It's visceral fat, wrapped around your organs, and your scale can't detect it.
Clinical studies show Prolon specifically targets visceral and liver fat, reducing waist circumference where it matters most.3
4. Protects Every Pound Of Muscle You Have Built
After 40 you're already losing lean muscle every year. Most diets and GLP-1 medications accelerate that.
Prolon doesn't.
It is clinically shown to support lean muscle protection. The L-Drink in every daily box is specifically engineered to protect lean tissue while your body burns fat. 4
5. The Same Heart And Metabolic Benefits As 120 Days Of Mediterranean Diet
In just 20 days across four cycles, Prolon gives you the same cardiovascular benefits as 120 days of a Mediterranean diet, while still protecting muscle mass.5
Studies also show support for healthy metabolic markers that can include glucose, blood pressure, cholesterol, and triglycerides.
6. Helps Reduce The Mental Decline That Most People Blame On Age
By day 4 of Prolon’s 5-Day FMD, your brain shifts to running on ketones, a cleaner, more efficient fuel than glucose with neuroprotective properties. Many report sharper mental clarity and focus as a top benefit of prolonged fasting.6
7. Watch Your Skin Change Too, Because The Repair Is Happening At The Cellular Level
Forget anti-aging creams that only work on the surface.
Autophagy renews your skin from deep within, clearing damaged cells and regenerating from underneath.
After just one cycle, clinical measures show improved hydration and radiance. This isn't cosmetic, it's a biological change you can actually see.7
8. Prolon's 5-Day FMD Is Proven To Support Longevity
Prolon’s 5-Day Fasting Mimicking Diet (or FMD) is a patented, science-backed program.
Plant-based soups: Nourishing, nutrient-dense soups keep your body in fasting mode.
L-Bars: Give you energy while maintaining a fasting state.
L-Drink: Fuels your body and protects your muscles.
Herbal teas: Keep you hydrated and help manage hunger.
Supplements: Deliver essential vitamins and minerals.
9. Here’s What You Can Expect On Each Day
Day 1: Your glucose depletes and your body starts burning fat.
Day 2: Ketosis. Your body may shift into using fat as its primary fuel source.
Day 3: Autophagy activates; your cells begin cleaning the house.
Day 4: Deep cellular renewal begins and your mental clarity may peak.
Day 5: The transformation completes, but benefits continue through Day 6 and 7.
10. 25 Years Of Research. 1 Million Users. Here Is The Proof
Prolon is backed by over 41 clinical trials from institutions like USC, Stanford, and Mayo Clinic.
It's the world's first and only patented Fasting Mimicking Diet, supported by $48M+ in NIH research funding, 210+ patents, and thousands of healthcare professionals who recommend it.
Trusted by 1M+ real customers.
25+
Years of scientific research
Decades of studies on longevity and nutrition
47
Clinical trials
Conducted with world-leading institutions
18
Leading research institutions
Including USC, Stanford, Mayo Clinic, and more
200+
Pending or issued patents
For optimizing longevity and healthspan
1M + Happy customers
Prolon 5-Day Fasting Mimicking Diet
A curated mix of classic and bold powdered soups, plus a Fasting Shake and Fasting Bars to add variety during your fast.
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Fat loss with muscle protection
Cellular renewal via autophagy
Improved relationship with food
Renewed energy and mental clarity
What's inside the box?
The Prolon FMD includes everything you need for your five days of renewal. Just follow the meal guide and eat and drink what’s in each day’s box. The foods in each box are designed to nourish your body while staying below nutrient sensing pathways, so you stay in a fasting state, and get all the benefits of fasting. Learn more about what’s inside each kit below.
HSA/FSA eligible
HSA/FSA eligible
Pay for your Prolon purchase with qualifying HSA/FSA funds.
Programs like health savings accounts (HSA) and flexible spending accounts (FSA) enable individuals to allocate pre-tax money for qualified healthcare expenses. Prolon has partnered with Sika, allowing customers to use their HSA/FSA funds to purchase our science backed products.
Choose pay with Sika at checkout or learn more here.
Nutritional facts
Allergen information:
Contains tree nuts (almonds, macadamia nuts, pecans, coconut).
May contain soy.
Produced in a facility that processes tree nuts.
Disclaimer: Results may vary based on individual factors. Consult your healthcare provider before starting Prolon or any fasting program, especially if you have medical conditions. Statements have not been evaluated by the FDA; this is not intended to diagnose, treat, cure, or prevent any disease.