How much weight can one expect to lose, and will the individual be able to keep it off?

While the purpose of the Prolon diet is to trigger rejuvenation, weight loss may occur. Everyone is different, and weight loss depends on a number of factors. In a clinical study of participants who completed a 5-day Prolon cycle once a month for three months, the average weight loss at the end of the study was about 5.7 pounds. This was primarily abdominal fat, while lean body mass was preserved.