In our Mailbag: whether GLP-1s can be safely combined with the fasting-mimicking diet, if the days of carb counting are over for diabetes management, and how to advocate for yourself when your doctor has never heard of the FMD.
Myth or Method: Tongue scraping — does the Ayurvedic morning ritual really improve your breath, taste and gut health, or is your toothbrush enough?
Chapters:
0:00 Cold open: the longevity problem nobody is planning for
0:45 Melanie's 15-year dairy experiment
2:40 Why this episode is close to home
3:32 Myth or Method: Does tongue scraping actually work?
9:22 Meet Dr. William Hsu — endocrinologist, Joslin VP, L-Nutra CMO
10:35 The longevity hill he'll die on: will you have enough money to live to 110?
12:00 "We've cracked the code": nutrition as the new frontier of medicine
12:57 Lifespan vs. health span — and why modern medicine ignores the root cause
15:21 Should we treat aging like a disease?
18:49 Biological vs. chronological age: the car-mileage analogy
20:54 Polypharmacy, the "life sentence," and the patient who flew in on a private jet
27:12 Diabetes remission is now an official goal — the 2021 consensus
29:40 The Nobel Prize-winning science of nutrient restriction
31:31 The biosphere experiment — why continuous calorie restriction fails
34:02 Timing is the new dimension of nutrition
35:23 Intermittent fasting vs. periodic fasting — and how cells put up a shield
39:36 Longevity genes: how autophagy recycles the cell and makes it younger
44:49 Fasting is a double-edged sword — enter Valter Longo and fasting mimicking
48:08 Behavioral fasting vs. molecular fasting: a "stealth technology"
49:13 Why no single nutrient can do it — and the 40+ clinical trials behind the FMD
51:27 Remission through nutrition: the Crohn's data and the biological-age study
1:00:04 The benefit-risk case for 15 days a year
1:01:33 Dr. Hsu's why: his father's dementia
1:03:26 Three levels of benefit — metabolic, cellular and mental
1:07:07 Mailbag: Can GLP-1s be safely combined with the FMD?
1:12:12 Mailbag: Are the days of carb counting long gone?
1:17:59 Mailbag: My doctor doesn't know about the FMD. How do I advocate for myself?
1:19:29 Why he wants to be on the right side of history
Guest Bio: Dr. William Hsu is an endocrinologist and the Chief Medical Officer of L-Nutra, the longevity technology company behind Prolon, where he also founded its medical division, L-Nutra Health. He trained at Yale and Harvard and spent nearly two decades as a vice president at Harvard's Joslin Diabetes Center, one of the world's leading diabetes institutions. His work today centers on nutrition as medicine: using clinically validated fasting-mimicking protocols to address the root cause of age-related chronic disease and drive conditions like type 2 diabetes into remission.
Learn more about L-Nutra Health's medically supervised programs at https://l-nutrahealth.com/.
Have a longevity question? DM us @prolon on Instagram and you might make it into our mailbag!
Learn more about Prolon's 5-Day Fasting Mimicking Diet and longevity lifestyle products at prolonlife.com.
Almost Forever is brought to you by Prolon, powered by L-Nutra, the longevity technology company. This podcast is for entertainment purposes only and is not intended as medical advice, diagnosis, treatment, or a substitute for professional healthcare services. Always consult a qualified healthcare provider before making changes to your diet, exercise, supplement, or health routine. Guest views are their own and may not reflect those of Prolon or its parent company L-Nutra.
